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Lioresal General Information

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Lioresal is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury/disease). It works by helping to relax the muscles.

How to Use Lioresal

Take Lioresal by mouth with or without food as directed by your doctor, usually 3 times a day. To reduce your risk of side effects, your doctor may direct you to start Lioresal at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.

The dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than prescribed.

Use Lioresal regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not stop taking Lioresal without consulting your doctor. Some conditions may become worse when Lioresal is suddenly stopped. Also, you may experience withdrawal symptoms such as hallucinations and seizures. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.

It may take 1 to 2 months or longer to get the full benefit from Lioresal. Tell your doctor if your condition does not improve or if it worsens.

Lioresal Possible Side Effects

Drowsiness, dizziness, weakness, tiredness, headache, trouble sleeping, nausea, increased urination, or constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed Lioresal because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Lioresal do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion, depression, hallucinations).

A very serious allergic reaction to Lioresal is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Lioresal Precautions

Before taking Lioresal, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Lioresal may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using Lioresal, tell your doctor or pharmacist your medical history, especially of: kidney disease, mental/mood disorders (such as schizophrenia), brain disorders (such as seizures, stroke).

Lioresal may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of Lioresal, especially drowsiness and mental/mood changes (such as confusion).

During pregnancy, Lioresal should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Lioresal passes into breast milk. Consult your doctor before breast-feeding.

Lioresal Possible Intercations

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), other muscle relaxants, and narcotic pain relievers (such as codeine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness.

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